01 / Oncology
Carriers that switch on inside the tumour
Charge-shifting surfaces stay stealthy at physiological pH and become adhesive in the acidic tumour microenvironment. In orthotopic models this raised intratumoural payload concentration 6.2× versus untargeted carriers while liver accumulation fell by half.
- 6.2×
- Intratumoural payload
- -51%
- Hepatic accumulation